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Herpetic encephalitis

4 OMIM references -
5 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

CEDNIK syndrome

1 OMIM reference -
1 associated gene
34 signs/symptoms

Herpetic encephalitis

CEDNIK syndrome

TBK1	(UniProt - OMIM)		SNAP29	(UniProt - OMIM)
TICAM1	(UniProt - OMIM)
TLR3	(UniProt - OMIM)
TRAF3	(UniProt - OMIM)
UNC93B1	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TRAF3	(0.63)	SNAP29

Citations in the biomedical literature:

Herpetic encephalitis		CEDNIK syndrome
	Synonym(s): - HSV encephalitis - Herpes simplex encephalitis - Herpes simplex neuroinvasion		Synonym(s): - Cerebral dysgenesis-neuropathy-ichthyosis-palmoplantar keratoderma syndrome

	Classification (Orphanet): - Rare genetic disease - Rare immune disease - Rare infectious disease - Rare neurologic disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease - Rare skin disease

	Classification (ICD10): (no data available)		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: any age Type of inheritance: sporadic		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: any age Type of inheritance: autosomal recessive

	External references: 4 OMIM references - No MeSH references		External references: 1 OMIM reference - No MeSH references

CEDNIK syndrome
	Very frequent - Absent / hypotonic / flaccid abdominal wall muscles - Ataxia / incoordination / trouble of the equilibrium - Autosomal recessive inheritance - Downslanted palpebral fissures / anti-mongoloid slanting palpebral fissures - High nasal bridge - Hypertelorism - Ichthyosis / ichthyosiform dermatitis - Intellectual deficit / mental / psychomotor retardation / learning disability - Long face - Microcephaly - Palmoplantar hyperkeratosis / keratoderma Frequent - Abnormal eye movements / oculomotor disorder - Agyria / micro / pachy / macrogyria / lissencephaly / gyration / neuronal migration defect - Areflexia / hyporeflexia - Corpus callosum / septum pellucidum total / partial agenesis - Nerve conduction abnormality - Optic nerve anomaly / optic atrophy / anomaly of the papilla - Peripheral neuropathy Occasional - Abnormal dentition / dental position / implantation / unerupted / dental ankylosis - Anomalies of eyes and vision - Cardiomyopathy / hypertrophic / dilated - Dolichocephaly / scaphocephaly - Flattened nose - Gastrointestinal bleeding / hemorrhage / hematemesis / melena / rectorrhagia - Heart / cardiac failure - Late puberty / hypogonadism / hypogenitalism - Long / large ear - Nephrotic syndrome - Pericardium anomalies / pericarditis / absence / cysts / pericardial effusion - Proteinuria - Seizures / epilepsy / absences / spasms / status epilepticus - Sensorineural deafness / hearing loss - Short stature / dwarfism / nanism - Transient cerebral ischemia / stroke
Herpetic encephalitis
(no data available)